The men, aged between 16 and 35, suspected of having links with a criminal network involved in drug trafficking, were caught in possession of 512 kilos of kif, 94 kilos of tobacco leaves and 6 kilos of chira, said the National Police (DGSN) in a statement.
Police also seized several knives and two unlicensed motorbikes.
The main suspect, aged 30, has been on police wanted list over his connection with drug trafficking.
Morocco has beefed up its crackdown on drug trafficking leading to the arrest of hundreds of people across the country and at its international airports, mainly at Casablanca Mohammed V airport.
The North African country also has developed collaboration with European partners including Spain and France in cracking down on drug and human trafficking in North Africa and Europe.